Trey Nyoni opened the scoring in the 25th minute before Mason Greenwood equalised in the 29th. Substitute Alexander Isak restored Liverpool’s lead in the 69th, but Archie Brown levelled in the 73rd and Vedat Muriqi scored the winner in the 79th.
Liverpool suffer their first defeat after three wins in this European campaign. Fenerbahçe, meanwhile, secure their first victory of the league phase.