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Zambia: research on cholera vaccine response

Following research on immune responses to oral cholera vaccination in Zambia and its limitations.

Last updated : 1 key moments
Pipette photographed in June 2017. Generic illustration; this equipment is not identified as belonging to the study.
Pipette photographed in June 2017. Generic illustration; this equipment is not identified as belonging to the study. — Wetitpig0 / Wikimedia Commons — CC0 1.0 https://creativecommons.org/publicdomain/zero/1.0/ ; 24 juin 2017 ; redimensionnement.

Where things stand

An exploratory study published on 29 October follows 20 adults over 14 days.

Reported information

Small Lusaka study describes immune response to Euvichol

A study published in BMC Research Notes on 29 October 2026 examines 20 adults in Lusaka: 15 given one Euvichol dose and five unvaccinated controls, followed for 14 days.

Pipette photographed in June 2017. Generic illustration; this equipment is not identified as belonging to the study.
Pipette photographed in June 2017. Generic illustration; this equipment is not identified as belonging to the study. — Wetitpig0 / Wikimedia Commons — CC0 1.0 https://creativecommons.org/publicdomain/zero/1.0/ ; 24 juin 2017 ; redimensionnement.

The authors report increases in two immune signalling molecules, IL-21 and BAFF, among vaccinated participants. Most other markers remained unchanged.

The small sample and short follow-up limit the findings. This work describes biological markers; it does not measure clinical protection against cholera.

Sources 2